The genetic component of narcolepsy may exist, although it does not exactly follow a straightforward pattern. A family member with narcolepsy is present in around 10–20% of narcoleptics, indicating a hereditary tendency. Narcolepsy is frequently associated with a lack of orexin (hypocretin), and several genetic variables, including the HLA-DQB1*06:02 gene, raise the likelihood of the illness. But environmental factors like trauma or infections can also cause the illness to start. Modafinil, also known as Modalert 200, is a drug that is frequently used to treat symptoms such as excessive daytime drowsiness and improve wakefulness; however, it does not address the underlying genetic reasons. Early identification and treatment of narcolepsy can be aided by knowledge of the environmental and genetic variables that contribute to the condition.
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